World, Americas, Special Report

[ms-marvelesold]

The H1N1 influenza pandemic in 2009-2010, for example, was caused by a virus that turned out to be a genetic hodgepodge, fashioned from bits and pieces of North American, European, and Asian swine viruses, with some North American avian influenza and a segment of human influenza mixed in for good measure. And now, a study published June 5 in the journal mBio contains the worrisome news that in the future, we may have more to worry about than just swine, poultry or avian flu. Researchers have found a set of flu strains, avian in origin, that have jumped from swine to dogs in China, and then have reassorted with dog viruses, to produce several new canine flu strains in that country. Adolfo Garcia-Sastre, the study's corresponding author. He's director of the Global Health and Emerging Pathogens Institute and principal investigator at the Center for Research on Influenza Pathogenesis, Icahn School of Medicine at Mount Sinai in New York City. All this suggests potentially more opportunities for several viral strains to mix, circulate and undergo reassortment which we believe increase the chance of spillover to human hosts, given enough contact and opportunity," according to Runstadler. "As an example, equine flu H3N8 can infect dogs, but the infection never spreads to another dog with one exception," Dubovi writes. "In 2004 an equine origin H3N8 was found in dogs. The opportunity for other jumps was there, but the unique changes needed to do it successfully are exceedingly rare by way of mutations.




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