Many of these chemicals are called esters. For example, the ester called Octyl Acetate (CH3COOC8H17) is a fundamental component in orange flavor. The ester called isoamyl acetate (CH3COOC5H11) is a fundamental component of banana flavor. If you add these esters to a product, the product will taste, to some degree, like orange or banana. To make more realistic flavors you add other chemicals in the correct proportions to get closer and closer to the real thing. You can do that by trial. Error or by chemical analysis of the real thing. There are hundreds of chemicals known to be flavoring agents. It's interesting that they are normally mixed to create "known" tastes. People make artificial grape, cherry, orange, banana, apple, etc. flavors, but it is very rare to mix up something that no one has ever tasted before. But it can and does happen occasionally - take Juicy Fruit gum as an example! How does the sense of smell work? How do scratch-and-sniff stickers work?
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